The Collaboration for Evidence-Based Healthcare in Africa (CEBHA) is a network of institutions in Africa and Europe that aim to support African health systems to work in evidence-based ways through the promotion of best available evidence in clinical healthcare and individual patient care and the fostering of South-South as well as North-South cooperation. These goals of CEBHA have recently been broadened to include public health activities in the Collaboration for Evidence-Based Healthcare and Public Health (CEBHA+, website under development) through a grant by the German Federal Ministry of Education and Research.